产品货号：
Z13023
中文名称：
CD209抗体
英文名称：
Anti-CD209 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD209 Antibody |
| 指标别名 | CD209;CD209 antigen;CD209 molecule;CDSIGN;CLEC4L;DC SIGN;DC SIGN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | CD209 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human CD209. |
| 计算分子量 | 46KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 (Cluster of Differentiation 209) is a protein which in humans is encoded by the CD209 gene.This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages.The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health.The protein is organized into three distinct domains:an N-terminal transmembrane domain,a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain.The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells.The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity.Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability.This gene is closely related in terms of both sequence and function to a neighboring gene.DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution.Alternative splicing results in multiple variants. |
| Uniprot ID | Q9NNX6 |
| 基因名全称 | CD209 antigen |
| 推荐稀释比 | WB,1:500～1:2000 |
相关搜索：CD209抗体，CD209多抗，Anti-CD209 Antibody